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Alexandros D. Polydorides, MD, PhD

2023 Dr. L. Clarke, Jr. and Elaine F. Stout Award

Dr. Alexandros D. Polydorides is Professor and Vice Chair for Clinical Research in the Department of Pathology, Molecular and Cell-Based Medicine at the Icahn School of Medicine at Mount Sinai and Attending Pathologist in the Division of Gastrointestinal Pathology at the Mount Sinai Hospital. He is also Professor in the Department of Medicine (Division of Gastroenterology), Professor in the Department of Medical Education, Master Educator at the Institute for Medical Education, and the Director of Undergraduate Medical Education in Pathology.

A native of Athens, Greece, he graduated from Princeton University in 1995 (summa cum laude in Molecular Biology) and the Tri-Institutional MD/PhD program in 2003, obtaining an MD from Weil Cornell Medical College and a PhD in Molecular Neuro-Oncology from Rockefeller University. He completed a Residency in Anatomic Pathology at New York Presbyterian Hospital/Weil Cornell Medical Center in 2006, where he was also Chief Resident, followed by a Fellowship in Oncologic Surgical Pathology at Memorial Sloan-Kettering Cancer Center in 2007 and a specialized Fellowship in Gastrointestinal Pathology at the University of Michigan in 2008.

He has clinical expertise in the diagnosis of dysplasia and carcinoma in the setting of chronic inflammatory disorders of the gastrointestinal tract such as Barrett esophagus, Helicobacter pylori gastritis, and idiopathic inflammatory bowel disease, including ulcerative colitis and Crohn disease. His research concerns the histomorphologic features and prognostic implications of various neoplasms and preneoplastic conditions in the tubular gastrointestinal tract. He has authored and co-authored numerous peer-reviewed original articles, expert reviews, and book chapters, including multiple titles and editions of the Diagnostic Pathology series.

Dr. Polydorides is a passionate teacher and mentor at all levels of training from aspiring medical students to pathology fellows and junior faculty. He received the Excellence in Teaching Award from the Institute for Medical Education at the Icahn School of Medicine at Mount Sinai in 2021. He lectures at national and international pathology meetings and courses and is an active member of many academic pathology societies, including USCAP and GIPS. He is a member of the editorial board for Modern Pathology and a Faculty member for Faculty Opinions.

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