Michael Miller, MD, PhD

2026 Ramzi S. Cotran Young Investigator Award

Michael Miller, MD, PhD grew up in Gambier, Ohio and obtained his bachelor’s degree from Grinnell College in Spanish and Biological Chemistry. Dr. Miller received combined MD/PhD training at the Dartmouth Geisel School of Medicine. Dr. Miller completed residency in anatomic pathology and fellowship in neuropathology at Brigham and Women’s Hospital and Boston Children’s Hospital, followed by postdoctoral research at Boston Children’s Hospital. During training, Dr. Miller developed single-cell genome sequencing methods and carried out the first studies of the genomes of single neurons in Alzheimer’s disease. For these advances, he was awarded the Doris Duke Foundation Clinical Scientist Development Award, an NIH K08 Mentored Clinical Scientist Research Career Development Award. Dr. Miller is now Assistant Professor of Pathology at Brigham and Women’s Hospital and Harvard Medical School.

Dr. Miller leads an NIH-funded research program focused on mechanisms of somatic mutation, cellular dysfunction, and protein misfolding in neurodegenerative disease and human aging. Dr. Miller’s research develops and utilizes advanced technology for somatic genomics as well as single-cell protein deposition pathology. He also developed and directs the Brain Donation Hub and the BWH Neuropathology Tissue Repository and Clinical Data Bank, enabling patients and families to impact research projects across pathology and other fields. Dr. Miller’s research activities are complemented by his clinical service in neuropathology, where he founded and directs the BWH Neurodegenerative Case Conference series, bringing together clinicians in multiple disciplines.

Dr. Miller has authored original research published in high-impact journals including New England Journal of Medicine, Nature, Nature Genetics, Cell, Science, Acta Neuropathologica, and Structure. He has been recognized by the NIH Director’s New Innovator Award (DP2), the Robert Terry Award (AANP), and as a mentor through the BWH Stanley Robbins Award.