Sponsored by the Brigham & Women’s Hospital and USCAP
The Ramzi S. Cotran Young Investigator Award was established by the USCAP Board of Directors to recognize a body of investigative work which has contributed significantly to the diagnosis and understanding of human disease. This award is restricted to USCAP members who are under the age of 45 and in good standing with USCAP for at least one year prior to receiving the award.
This important award is named after Dr. Ramzi S. Cotran, Past-President of USCAP, outstanding pathologist, person, and mentor. The award consists of a commemorative plaque and $5,000.
Selection Process
- Application form, completed and signed by the applicant
- Curriculum Vitae (CV)
- Letter from a nominating sponsor (not necessarily a USCAP member) summarizing the nominee’s qualifications for the award
- Supporting letter from an additional sponsor who must be a member of USCAP
Awardees are selected by The Ramzi S. Cotran Young Investigator Award Committee. Committee members rank the candidates and provide their assessment to the Committee Chair. The Chair notifies the Executive Vice President (EVP) of his/her selection. The EVP presents the individual to the Board of Directors for ratification (preferably at the Interim Meeting) and subsequently notifies the winner and arranges for the plaque and check. The awardee does not have to be present at the Annual Meeting and travel funds are not included.
Young Investigator Award Committee
The Committee consists of five (5) members:
a) Three members of the Board of Directors (one of whom will serve as Chair)
b) Two at-large members not currently serving on the Board of Directors Appointed members serve two-year staggered terms and may not serve a second consecutive term.
The Executive Committee at its Annual Meeting makes appointments to this committee.
Tjalling Bosse, MD, PhD
2023 Ramzi S. Cotran Young Investigator Award
Dr. Tjalling Bosse currently is an associate professor in the Department of Pathology, at the Leiden University Medical Centre (LUMC) in the Netherlands, where he combines clinical work, teaching and research. He received his M.D. degree in 2008 from the University of Amsterdam and a Ph.D. degree in 2006 from the Erasmus University in Rotterdam. He completed his pathology training at the LUMC, and subspecialized in gynecologic pathology during a fellowship at the Brigham and Women’s Hospital in Boston under supervision of Prof. Dr. Marisa R. Nucci. Upon return, he was certified as pathologist by the Royal Dutch Medical Association and became member of staff at the department of pathology of the LUMC.
Dr. Bosse currently leads a translational research program focused on gynecological cancers. He is lead pathologist for international randomized controlled clinical trials (PORTEC- and RAINBO-trials). His research currently has 3 active themes; 1) improving diagnostic accuracy by integrating molecular genetic features in endometrial carcinomas 2) identification of novel druggable targets within endometrial carcinoma and 3) utilizing deep-learning to improve diagnostic accuracy and identify novel prognostic and predictive biomarkers. His work has had major implications on the management of gynecologic cancer patients worldwide.
Since 2013, Dr. Bosse has published >120 articles covering a wide range of pathology oriented, investigative and clinical peer reviewed journals. Many were published as first or corresponding author in high impact journals including Journal of Clinical Oncology, Nature Communications and Lancet Digital Heath. He is a recognized (inter)national expert and invited speaker at masterclasses, specialized courses and state-of-the-art sessions. He serves on (inter)national guideline committees, authored five chapters of the WHO Classification of Tumours of Female Reproductive Organs 2020. He received many awards including a prestigious Young Investigator Grant by the Dutch Cancer Society (2016), The Helga Salvesen Award (2017) by the ESGO and the Jeremy Jass Prize for research excellence by the Journal of Pathology (2020).
He has a history of excellent fund-raising capacity, with almost continuous support by the prominent Dutch Cancer Society (raising >3M Euro grant money). Dr. Bosse successfully recruited and mentored many talented future pathologists and scientists and continuous to do so.
Previous Award Recipients
| 2022 | Peng Ji |
| 2021 | Lanjing “L.J.” Zhang |
| 2020 | David A. Solomon |
| 2019 | Laura D. Wood |
| 2018 | Lynette M. Sholl |
| 2017 | Anthony J. Gill |
| 2016 | Donna Hansel |
| 2015 | Charles Mullighan |
| 2014 | John Iafrate |
| 2013 | Celina Kleer |
| 2012 | Cristina Antonescu |
| 2011 | Shuji Ogino |
| 2010 | Jorge S. Reis-Filho |
| 2009 | Christine Lacobuzio-Donahue |
| 2008 | Anirban Maitra |
| 2007 | Arul M. Chinnaiyan |
| 2006 | Kojo S. J. Elenitoba-Johnson |
| 2005 | Marc Ladanyi |
| 2004 | Mark A. Rubin |
| 2003 | Julia A. Bridge |
| 2002 | Frederic G. Barr |
| 2001 | Ralph Hruban |
| 2000 | Mary Sunday |
| 1999 | Lawrence M. Weiss |
| 1998 | Cheryl L. Willman |
| 1997 | Christopher D.M. Fletcher |
| 1996 | James R. Downing |