Sponsored by the Brigham & Women’s Hospital and USCAP

The Ramzi S. Cotran Young Investigator Award was established by the USCAP Board of Directors to recognize a body of investigative work which has contributed significantly to the diagnosis and understanding of human disease. This award is restricted to USCAP members who are under the age of 45 at the time the award is given and in good standing with USCAP for at least one year prior to receiving the award.

This important award is named after Dr. Ramzi S. Cotran, Past-President of USCAP, outstanding pathologist, person, and mentor. The award consists of a commemorative plaque and $5,000.

Selection Process

  • Application form, completed and signed by the applicant
  • Curriculum Vitae (CV)
  • Letter from a nominating sponsor (not necessarily a USCAP member) summarizing the nominee’s qualifications for the award
  • Supporting letter from an additional sponsor who must be a member of USCAP

Awardees are selected by The Ramzi S. Cotran Young Investigator Award Committee. Committee members rank the candidates and provide their assessment to the Committee Chair. USCAP Staff then presents the individual to the Board of Directors for ratification and subsequently notifies the winner and arranges for the plaque and check. The awardee does not have to be present at the Annual Meeting and travel funds are not included.

Young Investigator Award Committee

The Committee consists of five (5) members:

a) Three members of the Board of Directors (one of whom will serve as Chair)

b) Two at-large members not currently serving on the Board of Directors Appointed members serve two-year staggered terms and may not serve a second consecutive term.

The Executive Committee at its Annual Meeting makes appointments to this committee.

The application window will close Tuesday, October 31, 2023, at 2PM EDT, 11AM PDT.

Tjalling Bosse, MD, PhD

2023 Ramzi S. Cotran Young Investigator Award

Dr. Tjalling Bosse currently is an associate professor in the Department of Pathology, at the Leiden University Medical Centre (LUMC) in the Netherlands, where he combines clinical work, teaching and research. He received his M.D. degree in 2008 from the University of Amsterdam and a Ph.D. degree in 2006 from the Erasmus University in Rotterdam. He completed his pathology training at the LUMC, and subspecialized in gynecologic pathology during a fellowship at the Brigham and Women’s Hospital in Boston under supervision of Prof. Dr. Marisa R. Nucci. Upon return, he was certified as pathologist by the Royal Dutch Medical Association and became member of staff at the department of pathology of the LUMC.

Dr. Bosse currently leads a translational research program focused on gynecological cancers. He is lead pathologist for international randomized controlled clinical trials (PORTEC- and RAINBO-trials). His research currently has 3 active themes; 1) improving diagnostic accuracy by integrating molecular genetic features in endometrial carcinomas 2) identification of novel druggable targets within endometrial carcinoma and 3) utilizing deep-learning to improve diagnostic accuracy and identify novel prognostic and predictive biomarkers. His work has had major implications on the management of gynecologic cancer patients worldwide.

Since 2013, Dr. Bosse has published >120 articles covering a wide range of pathology oriented, investigative and clinical peer reviewed journals. Many were published as first or corresponding author in high impact journals including Journal of Clinical Oncology, Nature Communications and Lancet Digital Heath. He is a recognized (inter)national expert and invited speaker at masterclasses, specialized courses and state-of-the-art sessions. He serves on (inter)national guideline committees, authored five chapters of the WHO Classification of Tumours of Female Reproductive Organs 2020. He received many awards including a prestigious Young Investigator Grant by the Dutch Cancer Society (2016), The Helga Salvesen Award (2017) by the ESGO and the Jeremy Jass Prize for research excellence by the Journal of Pathology (2020).

He has a history of excellent fund-raising capacity, with almost continuous support by the prominent Dutch Cancer Society (raising >3M Euro grant money). Dr. Bosse successfully recruited and mentored many talented future pathologists and scientists and continuous to do so.

Previous Award Recipients

2022 Peng Ji
2021 Lanjing “L.J.” Zhang
2020 David A. Solomon
2019 Laura D. Wood
2018 Lynette M. Sholl
2017 Anthony J. Gill
2016 Donna Hansel
2015 Charles Mullighan
2014 John Iafrate
2013 Celina Kleer
2012 Cristina Antonescu
2011 Shuji Ogino
2010 Jorge S. Reis-Filho
2009 Christine Lacobuzio-Donahue
2008 Anirban Maitra
2007 Arul M. Chinnaiyan
2006 Kojo S. J. Elenitoba-Johnson
2005 Marc Ladanyi
2004 Mark A. Rubin
2003 Julia A. Bridge
2002 Frederic G. Barr
2001 Ralph Hruban
2000 Mary Sunday
1999 Lawrence M. Weiss
1998 Cheryl L. Willman
1997 Christopher D.M. Fletcher
1996 James R. Downing