REPORT OF THE 96th ANNUAL MEETING OF
THE UNITED STATES AND CANADIAN ACADEMY OF
March 24-30, 2007 - San Diego, California
The 96th annual meeting of the USCAP was held in San Diego, California and was by
all accounts a resounding success. 3534 physician-pathologists were in
The General Registration of the meeting was the highest in the history of USCAP
attendance. It was the largest meeting of physician-pathologists in the history of pathology, ever,
anywhere, by anybody!! These attendance figures continue to make the annual meeting of the
Academy the largest gathering, by far, of physician-pathologists in the world. Indeed, for the past five
years we have regularly had 3100 or more in attendance. 684 (19.3%) of the
registrants/attendees at the San Diego meeting were from international countries outside of the US and
Canada. The countries (and the number of international visitors from each country) included:
Mexico (66), Japan (60), Spain (53), Brazil (42), United Kingdom (42), France (36), Italy (35), South
Korea (34) , Australia (34), Ireland (34), Netherlands (21), Germany (19), Argentina (18), Switzerland
(16), Turkey (16), Taiwan (15), Greece (11), Austria (11), Belgium (9) , Czech Republic , Norway,
Portugal , Chile, Columbia , Israel, China, Costa Rica, Denmark, Dominican Republic, Egypt, European
Union, Holland, Hong Kong, Hungary, Iceland, India, Iran, Jordan, Kuwait, Laos, Latvia, Lebanon,
Malaysia, New Zealand, Nigeria, Pakistan, Panama, Peru, Philippines, Poland, Qatar, Saudi Arabia,
Scotland, Serbia, Slovakia, Slovenia, Singapore, Sweden, Thailand, Uruguay, Venezuela, Bolivia, Bosnia,
and the West Indies. Thus, in toto, 684 international visitors from sixty-four countries outside of the
USA and Canada were in attendance (19.3% of our total registrants). In actuality,
approximately 5500 pathologists and colleagues/investigators throughout the world contributed to this
historic Annual Meeting (see index of the Program Book for names).
Of the 3534 registrants, 1903 were Regular/Sustaining members (54 %) and 1083 were Junior
members/students (also an all-time record attendance). There were 326 pathologists in practice who
were not members and 216 residents/fellows who were not members (yet). Thus
including the Resident Monitors and other students, there were 1083 residents/fellows at our meeting (an
all-time record; almost 10% more than last years all-time record). The percentage of house staff
attending the meeting who are members of the Academy are for the past seven years - 41% , 69%, 67%, 66%,
76%, 84%, 81%, respectively. This probably relates to the effective recruitment we have had of
pathology house staff/fellows/pathologists-in-training in the last 7 years. In July
1999 we had a total of 520 Junior Members; in the following seven years we recruited over 4200 additional
Junior Members (many of which have now become Regular Members). Our present "steady state" of Junior
Members is over 2400. Our total USCAP Membership is 10,500 physician-pathologists.
Dr. Henry Appelman (University of Michigan) served a distinguished and quite
active term as President of the USCAP. He turned over the gavel and the Presidency to Dr. Chris Crum
(Harvard: Brigham & Women's) as the new President of the Academy.
2400 scientific abstracts were submitted for evaluation; an all-time record in
submitted abstracts (all submitted electronically). The quality of the submitted abstracts
remains very high. A record 1660 were accepted after "blind" peer review (70 % acceptance). The review
is conducted by at least 4 individuals from the Academy (3 "experts" in the area and one from the Academy
Education Committee). The percentage of acceptance is generally dependent upon the space available at
the hotel (which is usually booked 5-6 years in advance of the meeting). abstracts were presented
in the poster sessions (a record) and 280 as platform sessions. We try to accommodate as many quality
poster sessions as space allows. Abstracts were submitted from throughout the world (from approximately
40 countries and about 350 academic medical centers and institutions). This was the sixth year for the
USCAP to have electronic submission of our scientific abstracts (in conjunction with Marathon, Inc).
These scientific abstracts are now online searchable by topic, disease, word, technique, author,
institution, etc (www.uscap.org). The USCAP website: www.uscap.org consistently has the last three years of scientific
abstracts (approximately 5000) which are now searchable by topic, disease, author, etc for the last 3
As noted before, 1083 pathologists-in-training and students attended the various
portions of the meeting. 55% of ALL submitted scientific abstracts had a first author who is a
pathologist-in-training (compared to 38%, 43% and 53% the last three years). (this does not
count the house staff/fellows that are listed as second, third, etc authors). Over 400 Stowell-Orbison Abstracts were submitted. 230 were accepted for the
Stowell-Orbison competition, and an additional two hundred were accepted as regular abstracts. Once
again, the "scores" for the accepted Stowell-Orbisons were actually higher than the scores for the
"regular" abstracts accepted for presentation (i.e, Non-Stowell-Orbison). There were four co-equal
Stowell-Orbison Awards presented and four Certificates of Merit.
The recipients, in alphabetical order of first authors name, of the
Stowell-Orbison Awards are:
Alpha-Actinin-4 Defficient Mice Develop Focal and Segmental Glomerulosclerosis
with Features of Collapsing Glomerulopathy
S Alwaheeb, JM Henderson, A Weins, SV Dandapani, MR Pollak, Brigham and
Women's Hospital, Boston, MA; Brigham and Women's Hospital/Harvard Institutes of Medicine, Boston,
TMPRSS2-ERG Fusion Prostate Cancer: An Early
Molecular Event Associated with Invasion
S Perner, J-M Mosquera, F Demichelis, MD Hofer, PL Paris, J Simko, C Collins, TA
Bismar, AM Chinnaiyan, AM De Marzo, MA Rubin, Brigham & Women's Hospital, Harvard Medical
School, Boston, MA; University of Ulm, Ulm, Germany; Dana Farber Cancer Institute, Boston, MA; University
of California, San Francisco, CA; McGill University Faculty of Medicine, Montreal, QC, Canada; Johns
Hopkins University School of Medicine & Bloomberg School of Public Health, Baltimore, MD; ITC-Irst,
Povo (Trento), Italy; University of Michigan Medical School, Ann Arbor, MI
Prevention of Acute Graft-Versus-Host Disease by Blocking T Cell Entry to
Secondary Lymphoid Organs
S Schulz, A Beilhack, J Baker, G Beilhack, R Nishimura, G Landan, E Baker, EI
Herman, EC Butcher, CH Contag, RS Negrin, Stanford University, Stanford, CA; Technical University
Munich, Munich, Bavaria, Germany
Julie M. Wu
Heterogeneity of Breast Cancer Metastases: A Rapid Autopsy Study Using Matched
Primary-Metastases Tissue Microarrays
JM Wu, M Halushka, D Molavi, J Fetting, NE Davidson, AM De Marzo, MJ Fackler, S
Sukumar, P Argani , Johns Hopkins Medical Institutions, Baltimore, MD
Certificates of Merit
Jessica B. Chan
Prostate Stem Cell Antigen as an Adjunctive Marker for Transitional Cell Carcinoma
in Urine Cytology Specimens
JB Chan, B Shurtleff, R Reiter, JY Rao, University of California, Los Angeles, Los Angeles, CA
Paul S. Furmanczyk
Characterization of the Phosphatidylinositol 3-Kinase Pathway in
Neurofibromatosis-1 Associated Tumors
PS Furmanczyk, E Downs-Kelly, JR Goldblum, RB West, M van de Rijn, BP Rubin,
University of Washington Medical Center, Seattle, WA; Cleveland Clinic Foundation, Cleveland, OH;
Stanford University Medical Center, Stanford, CA
O. Hans Iwenofu
Phospho-S6 Ribosomal Protein: A Potential New Predictive Sarcoma Marker for
Targeted mTOR Therapy
OH Iwenofu, DG Goodwin, A Staddon, HM Haupt, JJ Brooks, Pennsylvania
Hospital of the University of Pennsylvania Health System, Philadelphia, PA; Pennsylvania Hospital,
Immunohistochemical Expression of Vitamin D Receptor Correlates with Decreased
Immunohistochemical Activity of Peroxisome Proliferator-Activated Receptor-a in Steatohepatitis
Q Liu, LK Campbell, M Tretiakova, C Gong, J Hart, The University of
Chicago Hospitals, Chicago, IL
USCAP/ADASP Autopsy Award
G. L. DiSibio
A Retrospective Correlation of Primary Cancers with Their Metastatic Sites at
GL diSibio, SW French , Harbor-UCLA Medical Center, Torrance, CA
USCAP/ADASP Surgical Pathology Award
E. M. Manion
Mandatory Second Opinion in Surgical Pathology Referral Material
EM Manion, MB Cohen, JA Weydert , University of Iowa Carver College of
Medicine, Iowa City, IA
672 registrants attended the Long Course entitled "Targeted Therapies of Cancer:
New Roles for Pathologists" directed by Drs. Marc Ladanyi (Memorial Sloan-Kettering Cancer Center) and
Allen Gown (PhenoPath Labs) . Early perusals of the critique form show that this course was very
well done and very well liked by the plus registrants. The syllabus was
complete/"long" (200 pages in length) and this Long Course includes a CD packed full of several hundred
images. This Long Course will be published in the next year in Modern Pathology.(Last year's
Long Course on Diseases of the Liver and Pancreas is in the February 07 issue of Modern Pathology).
Sixty half-day Short Courses were presented and set an all-time record of
attendance (with a total registration of Short Courses taken being 4923 -that is the number
of courses attended times the number of attendees at these sessions (this is 200 more than the previous
record, held by our Chicago meeting in 2002); an overall average of about 82 pathologists/per Short
Course offering). From 1999 to the present time, the Academy has had regularly over 4000 in total
registration each year. Virtually all of our Short Courses have CD's (with 95% having post-conference
CDs) and several have "Virtual Slides". Also what was amazing and wonderful was the fact that on Friday
afternoon, last day of the meeting (I attended all the Friday PM Short Courses) over 500 people were
still in attendance going to the Friday afternoon Short Courses!
Two all-day Special Courses were offered: one on Introductory Molecular
Pathology (headed by Drs. Julia Bridge (Univ. Nebraska), and Margie Scott (Univ. Arkansas) attracting
153 registrants on Thursday. For the third year in a row this course has a CD in addition to the
extensive syllabus. The ongoing Advanced Molecular Pathology course (headed by Dr. Frederic Barr, Univ.
of Pennsylvania) on Tuesday attracted 258 registrants and included a CD in addition to the extensive
Twenty - Four Companion Societies presented their educational endeavors on Saturday night and
Sunday. The total registrations (number of attendees times the number of Companion
Societies) was 2347, second highest in our history, after last years all-time record (2371).
For the past five years all of the Companion Societies and evening Specialty
Conferences' handouts/syllabus have been placed on our website. (www.uscap.org) after the Annual meeting. This year was our second
year for the Companions and the Specialties to go "paperless". All of the Companion Society handouts
were on our USCAP Website at least 2-3 weeks before the meeting, and the Specialty Sessions had their
unknowns (i.e., Clinical history and unknown slides) up more than one month before the Annual meeting,
with the answers (i.e., text, powerpoints, references, answers, etc) up the morning after that evening
Specialty Conference. Two additional Companion's will be added next year: The American Society of
Cytopathology (Sunday night) and the American Association of Neuropathologists (Saturday night); thus we
will have 26 Companion Societies represented.
The Nathan Kaufman Timely Topic Lecture was given by Dr. Steven L. Kunkel,
Endowed Professor of Pathology, University of Michigan. The title of his lecture was " Inflammatory Keys
to Chronic Diseases " (a very timely topic to be sure!). His lecture was elegant, timely, and very well
received by the appreciative audience. He made us proud to be called "pathologist". (see www.uscap.org for biosketch).
Dr. Virginia LiVolsi, Professor of Pathology, University of Pennsylvania
presented the Maude Abbott Lecture. Her topic was "C Cell Lesions of the Thyroid: From Discovery to
Molecular Biology." This elegant and wonderful lecture was also well attended. Her's was truly an
outstanding presentation, an educational demonstration of superb organization and clarity. It was also a
great historical review of this subject. (www.uscap.org)
The Distinguished Pathologists Award was presented this year to an
individual in recognition of distinguished service in the development of the discipline of pathology.
Dr. Peter Burger, Professor of Pathology at Johns Hopkins, recognized by the
Academy membership for his major and extensive contributions to pathology (especially neuropathology)
over the years. Please see the USCAP Website (www.uscap.org) for his biosketch.
The President's Award was presented this year to Jim Crimmins. His
dedication and work is way "above and beyond the call of duty". He received a very lengthy and vibrant
standing-ovation! (And deserved it!). Please see the USCAP Website of the 2006 Annual Meeting for
details about this outstanding and dedicated individual who have contributed so much to pathology
The F.K. Mostofi Distinguished Service Award went to Dr. Victor Reuter,
Sloan-Kettering Memorial Hospital, for his numerous important past activities in the USCAP including
being Chair of the USCAP Education Committee and the ad hoc Bylaws Committee, as well as multiple other
significant contributions to the Academy. (www.uscap.org)
The Ramzi Cotran Young Investigator Award was presented to Dr. Arul M.
Chinnaiyan , of the University of Michigan for his outstanding, cutting-edge work in the field of
the molecular basis of prostatic carcinoma. (www.uscap.org)
The recipient of the Castleman Award (for the best published paper in the
field of human pathology ) was Dr. Adebowale Adeniran, presently of MD Anderson for his paper
"Correlation between Genetic Alterations and Microscopic Features, Clinical Manifestations, and
Prognostic Characteristics of Thyroid Papillary Carcinomas" in the American Journal of Surgical Pathology
30(2): 216-222, 2006. This work was done while he was at the University of Cincinnati and in
conjunction with the University of Michigan. It must be noted that again the number of applications
for this prestigious award were numerous, with many outstanding individuals having papers published in
many outstanding journals.
The F. Stephen Vogel Award (for the most outstanding paper published in an Academy
journal by a pathologist-in-training ) went to Dr. Donna Hansel, presently of the Cleveland
Clinic for her paper "Telomere length variation in biliary tract metaplasia, dysplasia and carcinoma"
published in Modern Pathology (volume 19, pages 772-779, 2006). This work was done while she was at the
Johns Hopkins Hospital.
The 17 evening Specialty Conferences, which are organ-based, were held from
7:30-9:30 PM, which was a testimony to the continuing endurance of the meeting's registrants. All of the
evening Specialty Conferences are online on the Academy's website. For the past five years the unknowns
(i.e., clinical history and representative histologic images) are placed on our USCAP website several
weeks before the annual meeting, and the answers, complete text, references, etc are placed on our
website the next morning after the Specialty Conference for all throughout the world to enjoy.
Additional activities of the Academy have concentrated on the partnership
of our two academy journals with the most outstanding medical and science publishing group in the
world--Nature Publishing Group. Many of the top scientific breakthroughs of the 20th Century were first
reported in the journal - Nature (it is the world's foremost weekly scientific journal by impact
factor). Nature Publishing Group (NPG) publishes over 30 high profile society-owned or affiliated
journals and 7-8 of the top 20 in the world in impact factor. Both of our Academy's journals now offer 2
pages of free color per published article, rapid advance online publication available 6 weeks after
manuscript acceptance, increased international exposure, electronic table of content alerts delivered
directly to your inbox highlighting new content each month, online submission of manuscripts and
tracking, and reference cross-linking via CrossRef and MEDLINE. Powered by Naturejobs, the Career and
Recruitment division of the journal Nature, Pathologyjobs provides recruiters with unique vehicles to
advertise. Their Nature website is outstanding with free abstracts of all articles, integrated searches,
online archives of all full-text articles from 2000 available through a personal or institutional
subscription, and author index-which searches authors names across all available articles. This is a
very powerful force in research and education for our members to utilize. In addition, the scientific
abstracts for the past three years are now online and searchable. (Please see our USCAP and the Nature
Other educational endeavors by the USCAP this past year include:
By action of Council, the USCAP instituted a Strategic Planning Initiative
in 2003-2004 to look at the future of pathology and The Academy. Summer retreats (actually
advances) directed by Dr. Jeffrey Myers have continued, and implementation
of these educational goals and strategies are now underway. "Ideas, particularly bold ones, are hostage
to the quality of their execution". We happy to announce that the large majority of these have been
implemented at this time.
- The IAP Centennial Congress held in Montreal September 16-21, 2006. 2700 attendees (a record for the IAP Congresses) with individuals from almost 100 countries (also a record). A record number of scientific abstracts were submitted (from over 85 countries).
- The establishment of the eAcademy (go to:www.uscap.org For further information). This online, distance-learning tool, will render CME credit for a minor charge. This is under the Direction of Dr. John Sinard (Yale).
- The First American Board of Pathology-approved "Self Assessment Module" (SAM): Diagnostic Cytopathology 07.
- The development of the CME Portfolio for members.
- Continuing involvement in altruistic activities, including West and Sub-Saharan Africa.
- Continuing growth of the free USCAP "Knowledge Hub"
- Over 350 Virtual Slides are now up on the USCAP Website for free (IAP Centennial; Annual evening Specialty Conferences)
- The "Naturization"of Laboratory Investigation (watch for future developments of this type for Modern Pathology)
- The development of the Itinerary Planner (electronic planner) for the Annual Meeting
- Online Membership Renewal and Registration
- A Poster Creation Service and ability to demonstrate entire abstract online
- Pod casts of the IAP Centennial KeyNote Addresses
- Online Evaluation of all of the Academy's Courses
- A Booklet of "Take-home Pearls" from all the Companion and Specialty Conferences.
- And much more.
For the last three years, the Academy rolled out a number of new initiatives for
our Junior members including: Several programs for pathologists-in-training were instituted--
including the Fellowship Fair with 54 institutions to discuss hundreds of fellowships; the new evening
Specialty Conference just for house staff/fellows; and the House Staff Hospitality Room where Academy and
Pathology leaders from throughout North America were present to talk with the house staff.
The USCAP's annual summer pathology review course and update- Diagnostic
Pathology , with its fourteen outstanding faculty will be held in Banff, Alberta, Canada from July
14-20, 2007. It is Directed by Drs. Greg Fuller and Stuart Schnitt. (See www.uscap.org for
complete schedule). Last years course (06) came with a 1100 page handout and a 3800 image CD-ROM!
This was the third year for the USCAP Winter (January) Course entitled
"Diagnostic Cytopathology" under the initiation, leadership and direction of Dr. Celeste Powers
(Virginia Commonwealth University, Richmond). This 2 l/2 day weekend intense and advanced course
was held at the Sheraton San Key Resort, Clearwater Beach, Florida. The 700 plus page handout and the
extensive CD (with over a thousand images) were very well received. There were 80 individuals in
attendance. We will be doing another winter Diagnostic Cytopathology course next year in January 2007
probably to be held in the Southwest (Arizona probably)
The new educational initiative of the USCAP is Practical Pathology Seminars, in
its second year, under the direction of Dr. John Goldblum. It will be held from May 3-6, 2007 in
Cancun, Mexico at the JW Marriott Cancun Resort and Spa. Five short courses will be given on topics
including: Cytology, GI, Head and Neck lesions, Skin (Melanoma), and Bone by an outstanding faculty of
Next year's annual USCAP meeting will be held in Denver, Colorado, March 1-7,
2008 . The Long Course entitled "Renal and Urothelial Tumors "will be directed by Drs.
John Eble and David Grignon. As usual there will be an extensive handout/syllabus and a CD with a great
There are several additions to our USCAP Committees: Five new members of
the Education Committee (under the Direction of Dr. Jeffrey Myers ) are:
Drs. Ester Oliva (Mass General), Marie-Christine Aubry (Mayo), Jesse McKenney (Univ. Arkansas), Scott
Kilpatrick (N.Carolina), and Mike Morgan (Univ. S. Florida/Tampa). Last year, by action of our Long
Term Strategic Planning Initiatives under Dr. Jeffrey Myers, we added two Junior Members to the USCAP
Education Committee: Drs. Sigrid Wayne ( Univ. Iowa) and Michael Bennett ( Brigham & Women's
Hospital). They have now completed their two-year terms and we have chosen two new members: Drs.
Michael Tetzlaff (University of Pennsylvania) and Matthew Wasco (University of Michigan).
Dr. Richard Zarbo, Henry Ford Hospital is by vote of the membership the new
Vice-President of the Academy, and Dr. Victor Reuter is President-Elect. The newly elected (by the
Academy membership) Council members are: Drs. Jeffrey Myers (University of Michigan), Henry Tazelaar
(Mayo, Scottsdale, Arizona), and Mary Bronner (Cleveland Clinic).
Dr. Jack Strong (LSU) heads the Finance Committee and our newest members
are Drs. Janice Lage (MUSC), and Jim Linder (Univ. Nebraksa). The Publications Committee is chaired by
Dr. Allen Gown with Drs. Rick Fraser (McGill/Montreal) and Ron DeLellis (Brown/RI) as our newest
members. The newest members of the Ramzi Cotran Young Investigator Committee
are Drs. Jonathan Epstein (Johns Hopkins), and Peter Humphrey (Wash U). New Members of the Castleman Award Committee include: Drs. David Rimm (Yale), and Greg Lauwers (Mass
Gen). New members of the Vogel Award Committee are Drs. Jennifer Hunt
(Cleveland Clinic) and Gordon Yu (Univ. Penn). All of the members of the various USCAP Committees are
noted on our website (www.uscap.org).
The new at-large member of the Nominating Committee (under the Direction of
Dr. Henry Appelman) is Dr. Ed Gabrielson. If you have nominations for Council (or any available
committee position) please let the central Augusta office know (email@example.com).
Please check the USCAP Website (www.uscap.org) for an immense number of
educational materials which are free. Over five year's worth of evening Specialty Conferences and
Companion Society's materials are up as well over three dozen of excellent, ended Short Courses and
available to anyone who wishes to utilize them. In addition, as noted before, three successive years of
our scientific abstracts are now online and searchable, and can be downloaded, as well as many Short
Courses. That's over 5000 searchable cutting-edge scientific abstracts! We also have a Table of
Contents by 20 plus organ systems/subspecialties of our thousands of educational entries/modules for all
to have for free. Our USCAP Website continues to have record-setting hits with over 5.0 million hits in
January 2007 from almost 20,000 pathologists from throughout the world (85 countries) with over 500,000
total page views that month. (In March 07 the "hit" rate was over 9 million with over 22,000
pathologists involved and almost 600,000 page-downloads for that month alone)! The USCAP is happy to
provide this free altruistic service for pathologists throughout the world. Go to: www.uscap.org for the largest eBook in the history of anatomic and
diagnostic molecular pathology, for free!
At present the USCAP membership is 10,500 pathologists; over 2400 of those are Junior Members. We
continue to grow and be vibrant. We have added almost a thousand new members in the last 12 months
alone. It is clear that our colleagues in pathology are a very dedicated and professional lot. We are
proud to be associated with them.
Please contact me at firstname.lastname@example.org if you have any
suggestions of how we can make our educational programs more relevant to your practice needs.
Thanks for all your support for all those we serve--our patients, our physicians and our students.
Hope to see you in Cancun, Banff, Phoenix/Scottdale, and Denver.
Fred Silva, Secretary-Treasurer and Executive Vice President, USCAP
April 10, 2007